Neuro-oncology research

The main pathologies treated

The neurosurgery department is developing specific expertise in basic and clinical research into diffuse low-grade gliomas. On a regional level, a great deal of work is carried out in collaboration with the neurosurgery department at Hôpital Sainte-Anne and the UMR 8165 CNRS team. On the national level, Pr. Emmanuel Mandonnet is head of the RENOCLIP network’s “diffuse low-grade glioma” group. A large national database is currently under construction. In addition, an international GLIOCOM format has been created to share these data across Europe, within the European Low-Grade Glioma Network (ELGGN).

Collaborations

  • member of the POLA network (management of anaplastic oligodendrogliomas)
  • Saint-Louis molecular oncology platform (Dr Patricia de Cremoux and Dr Lehmann-Che)
  • Department of Pathological Anatomy, Hôpital Lariboisière, Pr Homa Adle Biassette

Research protocol

  • co-investigator of STIC RESECT on the value of 5-ALA fluorescence in glioblastoma surgery
  • co-investigator of the GLIADOME project (Gliomas Malins des Adolescents, 15-25 years)
  • co-investigator of the “OLA-TMZ-RTE-01” project Phase I/Iia study evaluating concomitant treatment with radiotherapy, olaparib and temozolomide in patients with unresectable high-grade glioma (Principal Investigator : Center Baclesse Caen Dr Dinu Stefan / IC / Lariboisière)